If the developer of モニカの脱出ゲーム release a PC client, you can definitely play it on PC without using an Android emulator. However, you can have a better gaming experience if you play モニカの脱出ゲーム on PC with LDPlayer.
With LDPlayer, you can both play モニカの脱出ゲーム on your big screen monitor with better graphics, and enhance your gaming experience.
If you need to operate some accurate clicks or combos in モニカの脱出ゲーム, you can write macros to trigger combos with one key using the macro feature in keyboard mapping panel. Very creative and time-saving!